ٶӣ ʱʱ ʱʱ̳ ʱʱ ʱʱʿƵ ʱʱʿ ʱʱʹ
 

Human Life Sciences Have Entered into the Era of MEBO¾Human Body Regeneration

Rongxiang Xu, M.D.

(Edited Talk Recorded on November 22, 2008)

(On November 22, 2008, Dr. Rongxiang Xu, gave a talk to all technical staff of MEBO International Group and explained in detail regarding the meaning of “MEBO-Human Body Regeneration,” the core message sent by MEBO to the world.)

I. The meaning of "MEBO-Human Body Regeneration: the Nature Creates Human Beings, MEBO Creates the Regeneration of Human Body."

Today we are going to clarify some issues related to the understanding MEBO’s core messages to the world. Here, let's start with the understanding of core messages on MEBO’s website. We have transcended from the historical understanding of regeneration to the current concept of "MEBO---the regeneration of human body.” We can say that MEBO is marching on the way to successfully reach goal of human body regeneration while most other scientists in the world are still engaged in cell cultivation in the lab. As you recall, in 2002 when embryonic stem cells were hot all over the world, MEBO proposed the concept of human body in situ regeneration via tissue-organs. At that time most of the scientists could not understand our concept at all. While many were excited about embryonic stem cells, MEBO already went way ahead in the frontier of life sciences by converting somatic cells into stem cells so as to form tissue-organs. While many still are trying to “re-program” the embryonic development process, MEBO are telling the world, “We have succeeded in vivo AND in vitro.” Last year, when it took others 5 years to turn into the direction of regenerative cloning via transformation of somatic cells as pointed by MEBO earlier, MEBO declared that it has succeeded in regenerative cloning of human tissues and organs in vivo and in vitro, which opened a brand new field of regenerative medicine and system. Even many scientists, not to mention lay people out there, were astonished by the progress made by MEBO. However, I believe that everyone here as insiders should understand this better. In general what we have accomplished are all achieved through regeneration. Today’s talk is the first part of a series of seminars to be held in the future: the Era of MEBO Human Body Regeneration. Through the clinical results we have already obtained we will trace back MEBO’s history. In the near future we will elucidate in detail each of the themes touched here.

As you can see, MEBO's logo and tag line stand for the regeneration of human body, through which we obtained all of our clinical achievements. This is not a propaganda slogan but a scientific declaration made by MEBO. Mother nature creates human beings, but she can not ensure how human beings can extend their life span. By following the law of nature, our humans should take on this task ourselves. This is also a historical responsibility shouldered by us at MEBO. Mother nature creates the human being, now MEBO, only MEBO, is focused on the regeneration of the whole human body. While everybody else in the world, no matter what field he/she is or a Nobel laureate or not, is still struggling for extending the life, MEBO has already achieved regeneration in higher vertebrates and humans. This is shocking, isn’t it? But we are not bragging here. For a long time MEBO has been working on the science of regeneration and applying it to the regeneration of the human body. How did MEBO achieve the human body regeneration? We have achieved the organ regeneration in the human body with life regenerative substances and technologies invented by MEBO (remember, we invented, not discovered that means differently from invention) and we have fully exploited our inventions to finally achieve renewal and Restorationof aged organs, to prevent and eradicate diseases, to ensure people's health and to extend people's life span so as to achieve longevity. Through this practice of human body regeneration MEBO has entered a brand new world of life extension.

The Technology of In Situ Regeneration of Tissue and Organ

The essence of human regeneration is: a live body, life regenerative substances (as the energy source for regeneration), and enabling techniques (to create regenerative conditions and environment).
The first key component is a live body. For a human the largest live body is the human body itself; and the smallest one is the cell. In 2002 when I announced that human somatic cells can function like stem cells to ensure regeneration of tissue and organ in the body, it caused quite a stir at that time. However, nobody negated or objected to this proposition because people couldn’t understand this then. Today, five years later, the world’s research has turned to the direction of regeneration of somatic cells, which IS the scientific exploratory route (from converting somatic cells to stem cells to form tissue and organ) what MEBO first pointed out and has been marching on to reach the goal of regeneration of human body.

The second key component is life regenerative substances, the regenerative energy source. Generally speaking, there are 6 types of essential nutrient substances that serve as the energy sources for the human body, including water, grains, etc. However, we are talking about the energy source for regeneration, which is different from the energy sources others are talking about. That is to say that when you add the regenerative energy source to the food, you will allow the somatic cells to regenerate physiologically. Without such regenerative substances, lost fingers will not re-grow, even in a suitable environment. The regenerative energy source is invented (not discovered) by MEBO, and is a kind of substances formed under specific conditions. This kind of substances can liberate the humankind. Everyone needs to take in the substances, and without them human beings would be facing early death because genetically the human life span should be 300 years. How to use the substances to benefit people in the world is in MEBO's business plan, which is realistic and feasible.

The third key component, regenerative technique is the method to ensure that the life regenerative substances effectively work on the regenerative cells in the body. For regeneration of the burn patients the regenerative technique is MEBT (moist exposed burns therapy), and for the regeneration of gastrointestinal (GI) tract, the regenerative technique is a specific micro-crystal formulation in our gastrointestinal capsules, in addition to the regenerative substances contained therein. The micro-crystals allow effective adhesion of regenerative substances to the GI lining. Some regenerative substances can be delivered orally, but not absorbed efficiently. Thus we developed carriers to deliver them systemically to the body, just like amino acids being delivered via carriers.
Combining these 3 key components, we achieved the regeneration of the human body.
We have also achieved the goals of anti-aging, restorationof aged organs, and essential recovery of patients. We believe that through such regeneration, people could eventually live for longer than 200 years. The nature creates human beings, and MEBO creates the regeneration of human body. Based on this understanding, everyone, the future will be amazing! We are pipe dreaming here. We have established a comprehensive application system to realize the dreams, ranging from each link in the chains to each technique in the whole regeneration process. We have truly achieved the integration of nature and humanity!

The Origin of Life and Its Regeneration
As just discussed, the creation of MEBO’s world of human body regeneration world is based on the combination of the three key components. If the human body didn’t possess the regenerative potential, we would not have been able to achieve the regeneration. Many scientists have been exploring the routes to regeneration, but have not succeeded so far. This is because they have been focusing on pathogenesis and on fighting diseases, instead of paying enough attention to the assurance of the human body’s abilities to regenerate. Many simply attribute such abilities of the human body to immunity: whether one gets a disease or not depends on his/her immunity. For the cytology, there has been little progress made since the discovery of the cell. Since the late 1980’s, people have started to hype the concept of stem cells again, and till now, there has been nothing but hot air, whether they are embryonic stem cells or induced pluripotent (iPS) cells. It is horrific that most main-stream scientist are focusing on changing the nature of life in order to obtain longevity. This approach is not based on the creation of life by the nature itself but on re-creation of human beings, which will never succeed. Further more, it is against humankind, and against the principles of life and the law of nature. We only know that human beings come from the nature. While people are trying to change the genetic core of life in an attempt to cure diseases, in my opinion, this approach is deemed to fail, as they do not know what consequences such changes will bring to human kind and how detrimental these consequences are. From one embryo developed into 6 trillion cells in the human body, it would be impossible for one to just take out one cell and, by controlling its genetic material, to create the entire human body or a human organ in vitro. This is because life is created from a live human body, not from a non-living entity. Although we say that the life created by nature is created from materials, such description is merely philosophical for a lack of full understanding of life itself. Based on what is learned about the development of the body, so far the extension of life can only be facilitated by the development of the body from a living being. The approach to curing disease by simply culturing cells and then transplanting would deem fail. Although we have also studied and achieved regeneration of tissue-organs in vitro, this cannot replace the organs in the body. The holly grail of human body regeneration is to regenerate in situ. The results we obtained from our basic research and clinical practice clearly show that all of our research performed in vitro is for the purpose of regeneration in situ and in vivo, serves as a reference to the culturing of organs in situ and in vivo, and as a yardstick to adjust and modify our approaches to regeneration in vivo. MEBO has pointed to the world the way by which our humans can exploit our own regenerative potential to regenerate tissue and organ in situ so as to resist aging, rejuvenate aged organs, prevent and eradicate diseases, and achieve longevity. We are not shouting slogans here but to present factual evidence to demonstrate such. What we are doing is in accordance with the law of nature, an extension of what the nature can do. The future of the world belongs to MEBO; and MEBO belongs to the world in the future.

Regenerative Life Extension and Recovery from Diseases

In today’s talk I combined the concepts in philosophy and those in life sciences, which can be called an “integration of nature and life” philosophical terms. Conceptually the traditional medicine is to control the diseases and quantitatively is to reduce the death rate. But in fact, it has not changed the human life fundamentally. Let's say: 500 died among 10,000 patients, 9,500 still alive; if without the medicines and treatments, 5,000 might die. Thus, in terms of life extension qualitatively nothing has been changed, just a reduction in the number of death. What we are working is an extension of life. Please keep in mind this very important concept. The medicine could change the life of sick people, but cannot do much about the lives of healthy people to whom it is not necessary to treat with medicine. The characteristics of life-extension do not depend on the characteristics of patients, but on how long/how well the healthy people can live. Generally, most people believe that aging is a rule of nature, but this is a misconception if analyzed based regeneration of life. To break such a “rule of nature” we need to look into the potential of a human life, which is the human body’s potential to regenerate. By exploiting such a potential of our body, MEBO achieved extension of life by using our life regenerative energy source and techniques to ensure extension of life, and to prolong life span. So far only MEBO has achieved such levels in the field of life sciences. No matter how advanced the current medicine is, it is only applicable to diseased people, not to the healthy population. The historical status of MEBO is not simply at the level of achievements in science and technology, but a new starting point for human life. MEBO has found the “entry point” to life extension¾prolonging human life span through human body regeneration. This is precisely what MEBO’s life regenerative science is all about!

II. MEBO’s Realization of Human Body Regeneration
To elucidate the core message of “Nature create human beings, and MEBO creates human body regeneration,” a conclusion we draw here, we will use a large amount of compelling facts, not empty theoretical research designs. So far, other than MEBO, few has demonstrated that they could achieve the regeneration of human body. There are some reports of research at the levels of in vitro cellular studies, which are regeneration of tissue and organ in situ and in vivo. The concept of regeneration In situ and in vivo requires that the regenerated tissues and organs must comply with the physiology of the human body. We have also conducted some in vitro cellular experiments that were merely used for mechanistic studies from certain angles. Clinical application to the regeneration of a human body can only be achieved by studying the regeneration in situ through the manifestations of the body itself.

1. Regeneration of Lost Fingers/Toes
We've achieved one knuckle of the finger regeneration firstly in the world.

The Basis and Challenges of Limb Regeneration
Since phalanges (finger bones) are developed from the blastoma which produced 206 pieces of bones each carrying specific information. The relationship among the 206 pieces of bones is a relationship of siblings, not a mother-daughter relationship. Take the fingers as an example. The index finger has 3 segments. When an infant is born, the distal phalange has not developed completely. Thus, if the infant’s tip of the distal phalange is accidentally cut off, the fingertip can still grow back. However, if the distal phalange has completely developed and most of it is severed, the distal phalange cannot grow back from the remaining middle phalange. This is because the relationship between the distal and middle phalanges is that of siblings, not derivatives of each other. This is the challenge facing limb regeneration across the interphalangeal joints, namely, how to develop a new generation of the bone. If the whole segment of the phalange is completely lost, even we would not be able to regenerate through the stem cells in situ. Nobody else in the world can do this, either. Although many are trying to manipulate embryonic stem cells this way or that way, what has been modified is the type of the cells. So far, no physiological tissues, not to mention organs, have been materialized from these experiments. Others are still imagining limb regeneration in a fully developed adult. We already achieved that in adults with most of their distal phalanges missing but regenerated after the treatment by us. Nobody else has achieved this level of regeneration!

The Differences Between Regeneration in situ and Healing
All medical professionals know that bones can grow rather fast, however, it seems impossible for muscles, nerves and physiological blood vessels to grow along with the bones. The regeneration we achieved should not be simply regarded as wound healing, since wound healing refers to the process by which a large amount of fibrous tissues emerge from the wound and epithelial cells spread to cover and close the wound. While the "regeneration" we are talking about here is different from that kind of patchy work. We allow the bones to grow slowly, along which muscles, nerves as well blood vessels also grow slowly. This way, the blood vessels will not grow chaotically as in the process of wound healing. We want to make sure that the growth follows the original physiological process, including regenerating in situ to re-produce the original skin, including identical fingerprints. Such an ability to regenerate is intrinsic to the human body itself, not one we created out of nowhere. What we provide are regenerative environment and conditions that of course include life regenerative substances and enabling techniques.
Talking of healing, there are actually quite a few modes of healing of wound injury, such as healing by bandaging therapy, healing by suture post operation, as well as spontaneous wound healing. However, under many circumstances it is very hard for the wound to heal. Our regenerative healing is to close the wound by exploiting the body’s intrinsic ability to regenerate. For example, diabetic ulcers cannot heal physiologically since the body’s metabolism is in disorder. However, we could achieve “regenerative healing” to close the wound by utilizing the body’s ability to regenerate. Please note that the “regenerative healing” we mention here is different from the “regenerative restoration (of the body’s physiological structure and function)” we mentioned elsewhere in this talk.

Regenerative Healing and Regenerative Restoration
You should know that regenerative healing and regenerative restoration are completely different from each other. Regenerative healing is the closure of the wound by using the body’s ability to regenerate. However, the function of the healed wound has some differences from the original part prior to the injury. Regenerative restoration requires a complete restoration of the original structure and function. We need to be precise with the terms here. Regenerative restoration and regenerative healing are 2 different concepts. Do not confuse them with each other. Regeneration of a lost finger is different from healing which has its own international standards. What we achieved here is a regenerative restoration with the same tissue structure as the original, even the cells are the same, or substantially the same as the original ones. Take a look at the bone at the amputation plane here. When the bone is severed, it will form an eschar to protect itself. But in the clinic doctors change the wound dressing everyday, resulting in the loss of the protective eschar, which in turn prevents the bone from growing further after it passes the peak of the growth. By doing this the doctors destroyed the foundation from which the bone can be regenerated. We were talking about regeneration of severed fingers just now. Actually no matter it is a finger or a toe, the distal, middle or proximal phalange, as long as there is a little bit bone remaining for the segment, this segment can be regenerated. This technique was first invented and developed by MEBO back in 1989. There was this patient who only had some bone stubble remaining on his distal phalange in his index finger. Eventually we successfully treated him and achieved regenerative restoration of his finger. After that, we introduced this technique to the students at the Second Training Session on Regeneration Medicine for Burns; and afterwards the students immediately applied the techniques in the clinic to the regeneration of lost fingers of many patients.

Scientific Significance of Regeneration of Lost Fingers
Since then, this technique was applied all over China and has become a routine treatment modality for regenerating lost limbs. Lost limb regeneration is still a dream for the scientists in the world. In 2007, the Science magazine published 25 scientific dreams to be realized in the future, one of which is lost limb regeneration. While others still regard this as a dream, we already achieved the dream. The regeneration of lost limbs we achieved here is not merely a clinical result. It represents a new scientific field. Don’t underestimate such “simple” regeneration of fingers, it overturns the traditional healing and confirms the existence of a “second life” for the human body. Regeneration of lost fingers includes the regeneration of four main types of tissues in the human body, such results indicating that it is not simply healing. We must use new terms to define these differences between regeneration and healing. Some suggested that we should compile a MEBO glossary. This is a good idea. We need to clarify that our lost finger regeneration is a process of regenerative restoration by which a new, complete finger, as directed by the body, is regenerated from the wound of the injured finger with complete restoration of structure and function, such as allowing the reconnection of the regenerated blood vessels with those of the original ones without alteration in position or function. This process is not an issue of wound healing, but a process of gradual growth forward. How did it happen? We believe that such a regenerative growth stems from the development of regenerative cells on the wound that follows the embryonic development process in situ. Quantitatively, we have obtained tens of thousands clinical cases on finger/toe regeneration that have been reported. Please keep in mind that scientifically this represents the highest level and indicates that the human body can regenerate, as the regenerated fingers have the same shape, function, sensitivity, and sense of pressure as those of the original fingers or toes. Our science is developed based on real life (clinical) practice, not on imagination. Compared to the clinical results obtained by others, ours are in the frontiers. We have reached the goal of tissue/organ regeneration while others are still exploring, searching for the route to reach this goal.

2. Regeneration of Soft Tissue and Skin from Exposed Bone
Regeneration and Regenerative Derivation
Here is a new concept of regenerative derivation. As we said, regeneration of lost fingers is based on residual viable tissues on the wound, and is an extension of the residual original tissue structure. However, the fact that we could regenerate new soft tissue and skin upon exposed bone indicates that there exists another type of regenerative potential in the body, a potential of regenerative derivation. As you see, the soft tissue does not grow from the surface of the bone, but from cells in the tissue of bone marrow. First, bone marrow cells form soft tissue on the surface of the bone. Please note that such soft tissue is different from granulation tissue, because the inside of the granulation tissue is disorderly whereas inside the soft tissue the various types of tissues assume orderly structures. Back in 1996, in Xiangfan, Hubei Province, we observed and studied this phenomenon during the treatment of a severely burnt patient. The burn wounds of the patient reached the bone (tibia of his leg leg) and caused the exposure of his tibia. You all knew that by drilling holes on the bone, granulation tissue can grow from the holes, a routine techniques in orthopedics. However the granulation tissue ages quickly and soon stops developing. By using our regenerative therapy we could allow granulation tissue to grow from the holes and gradually develop into soft tissue and the skin. After this success, we conducted formal clinical studies in Hunan Province and video-recorded the whole process so as to keep track of the process of granulation tissue growth and analyze it histologically to determine what types of cells performed the functions. When we showed the pictures of the tissue slices to an expert in histology, she thought that the tissues were from the skin of a fetus! When we told her that this tissue was from the regenerated skin grown from drilled holes of the bone of a burn patient, she was shocked and stated that if this were true, it would cause a major change in science. Ever since then extensive clinical application of our regenerative therapy was spread all over China. Later by using the same techniques we successfully regenerated new skin from wound patients’ exposed skull. These cases indicate that the regeneration we achieved is not simply by drilling holes on the bone and growing granulation tissue from the holes, but by regenerating soft tissue and skin via regenerative derivation from bone marrow tissue cells under the life regenerative conditions we created on the wound. We stress that derivation follows regeneration, which is the intrinsic ability of the body. These results we obtained on regenerative restoration and derivation demonstrate that humans possess a function of embryonic development for the second time in their lives.
Currently many in the field are raving about induction of bone marrow cells. As a matter of fact, what they obtained are just transformed cells that did not form any tissue or organ. By contrast, we already successfully achieved regeneration in the clinic and our results are not from observation of cells in in vitro experiments, but based on examination and analysis of cells in the tissue samples obtained from our clinical studies. Our theories are formed based on clinical practice, and then applied successfully back to the clinical practice. In cases we studied, the nascent granulation tissue already contained fibroblasts and keratin-19 expressing embryonic epidermal stem cells, which continued to differentiate to eventually form the skin. These cases of regenerative derivation also indicate that scientifically we have already surpassed the previous levels of simple regeneration in situ. On top of regeneration in situ, we also achieved regenerative derivation. These results are not simply clinical data obtained. These results demonstrate that when human tissue is injured or lost, under the direction of the brain, the tissue can be regenerated through deviation (from other types of tissue) by following life’s intrinsic characteristics of maintaining its integrity. The topic of regenerative derivation is very important and needs to be further studied inside MEBO.
To give you another example, at a conference held in 1997 we reported these clinical results and concluded that for large-area 3rd degree burns new skin can be regenerated when the skin is completely destroyed. Soon afterwards our conclusion was validated in Taishan Medical College (Shandong Province) on a burn patient who suffered 80% TBSA and could not grow new skin after surgical excision of eschar. By using our regenerative therapy, a new skin organ was regenerated on the muscle at the wound after 112 days (post injury).

3. New Skin Regenerated from Burn, Trauma and Ulcer Wounds.
Regeneration and Regenerative Restoration of the Skin
The regeneration of full-thickness is a regenerative process. However such regenerated skin is not completely identical to the original skin. Only the new skin regenerated from the wound of superficial second-degree or the superficial type of deep second-degree burns is the same as the original skin. Although the new skin regenerated from the wound of the deep type of deep second-degree or third-degree burns is not exactly the same as the original skin, the epidermis, dermis and skin appendages of the new skin are physiologically connected with the original (survived) wound tissues and possess the same physiological functions. We don’t call such regeneration “regenerative restoration” because the regenerated skin, albeit new, is not completely identical to the original skin. Nonetheless. we have succeeded in regeneration of new skin locally and throughout the whole body, achieving regenerative restoration for the wound of superficial second-degree or the superficial type of deep second-degree burns, and regeneration of new skin for the wounds deeper. Thus, we can say that for the first time in human history the treatment of burn wounds has entered the scientific track of organ regeneration which leads to the most ideal and complete recovery. This touches upon not just the issues of the wound bed or simple regeneration, rather, an issue related to the whole medical system. On our part we initiated and attempted to reform the medical system. We have also achieved regeneration of trauma wounds and obtained a lot of results. Further, for various types of surface ulcers, which are considered non-healable by others, we also achieved regenerative healing.

4. Regenerative Restoration of Ulcerative and Inflammatory Gastro-intestines
Regenerative Restoration of Internal Organs in situ

As you can see from the slides, we have achieved regenerative restoration of gastro-intestines (GI) that have been ulcerative and inflammatory. Note that here I do not include GI with polypus, since we have not got enough and precise data. However, our preliminary data show that some polypus shrunk after treatment with our regenerative therapy. What we are quite sure about is the regenerative restoration of ulcerative and inflammatory GI. The world market for GI drugs is more than $270 billion. However, none of the drugs could restore the original structure and function of the ulcer wounds. The drugs could eliminate inflammation but not completely eradicate the disease (except for acute inflammation). Some drugs are quite effective in pain relief but etc, but they cannot restore the gastro-intestines completely. Compared at the levels of clinical efficacy, what we could achieve with MEBO regenerative therapy is unsurpassable. Evaluated scientifically, the regeneration of GI provides direct evidence for the regeneration of the internal organs. It would be quite difficult to obtain direct evidence of regeneration of the liver and kidney in a human body; but we could easily obtain the evidence from the GI tract. The regenerative restoration of the 4 major tissue types is representative of many characteristics of the internal organs. When we mention ulcer, let’s not just focus on the mucosa. Rather, we should think about the whole gastrointestinal wall which, if the ulcer gets worse, will perforate. In the body gastrointestinal mucosa is an organ for digestion and absorption. However, how each substance is absorbed all depends on the functional organs underneath the mucusa. The current treatment modalities in the world are all focused on the treatment of diseases with a disregard for the restoration of function. To them, it would be satisfactory just to close the wounds. We not only repair the wounds but also restore the structure and function of the organ.

5. Regenerative Restoration of Injured and Defective Tissue and Organ
There are large organs as well as small organs in the human body. Our focus is on the concept proposed by us—tissue-organ—which is a tissue unit composed of different types of cells with certain physiological function or functions.
When an tissue or an organ is injured or defective, we could restore its structure and function through regeneration. For example, when soft tissue is injured or lost, we could achieve restorative regeneration of the wound. Remember the May 12 (2008) earthquake victim who was wounded with a loss of a substantial piece of the skin and soft tissue on her forehead, exposing the skull. By using our regenerative therapy with MEBO Wound Dressing, she could recover with complete regenerative restoration of the soft tissue and skin, just like regenerative restoration of the burn wounds we talked about earlier. This is a major milestone in the treatment of trauma wounds.

6. Regenerative Healing of 3 Types of Surface Ulcer Including Diabetic Ulcer
Regeneration and Metabolism of Ulcer Wounds

Diabetic ulcer is associated with metabolism, whereas lower extremity ulcer is associated with nutrition in the body. For roentgen ulcer, nobody can deal with it except MEBO. Our solution to the problem is regeneration. Although the skin is ulcerative, the tissues underneath the wound bed still retain a potential to regenerate. We created regeneration of wound by providing our regenerative energy source and by exploiting the regenerative cells at the wound site. Of course, we will further explore the characteristics of such regenerative cells and to find out the differences between these cells and normal cells. Interestingly, these cells on the ulcer wound do not absorb normal energy or nutrients, but they could still regenerate to heal the wound. These results revealed many interesting aspects that are worth our further exploration. We are quite sure that the metabolism at the wound site is different from normal metabolism. To give you an example here. As you know, trauma patients who suffered from hepatophyma due to severe malnutrition have to be salvaged by injection of fat emulsion so as to provide energy to the body. Thus the source of the energy is not dependent on insulin as glucose needs insulin whereas fat emulsion does not. This is illuminating. MEBO also discovered that the regenerative cells obtain energy via uptake by absorption. We can say that in the body, providing energy via absorption of fat emulsion opens up a metabolic channel independent from insulin. While many regard the treatment of diabetic ulcers a major challenge, to us it is quite easy to tackle. Johnson & Johnson spent hundreds of millions to develop a new drug, which could only deal with diabetic ulcer with wound size below 5 centimeters in diameter and the efficacy is only 40%, which is way below the efficacy we achieved using MEBO regenerative therapy. While these 3 kinds of surface ulcers are considered as major medical challenges in the world, clinically we demonstrated that these 3 ulcers can heal through regeneration. For roentgen ulcer, when we applied MEBO Wound Ointment to the wound, new skin starts to grow. As revealed later, in our mechanistic studies of cancer cells, MEBO regenerative substances act directly on the cells by entering into the inside of the cell, not on the surface of the cell membrane. Above all this, what we achieved brings great hopes to many patients.

7. Regenerative Healing of Skin Cancer
Regeneration and Anti-Cancer

It is generally known that skin cancer not only does not heal but can also metastasize. Over the years MEBO has used the regenerative therapy to treat skin cancer and accumulated over 100 cases. Our success rate is virtually 100%. Skin cancer itself is a type of skin wound, the treatment of which we have a lot of confidence in. To us, the treatment of skin cancer wounds is just “a piece of cake.” But the treatment of skin cancer can become quite complicated when you try to follow the anti-cancer theories. In our view, just like what we observed in our experiments of cancer cells in vitro, upon absorption of our regenerative substances, cancer cells committed suicide while normal cells continue to grow.

8. Eradication of Tough Organ Diseases through Regeneration
MEBO can also convert many tough organ diseases, such as type II diabetes, cardiovascular diseases and liver diseases, into curable diseases. Generally speaking, to many doctors it can be very difficult to eradicate these diseases. To us, we could gradually renew the cells in these organs, thereby converting these diseases from tough to easy ones. We have already conducted a lot of experiments in these areas. Many diseases, such as coronary artery disease which is due to problems in cardiac muscles, such as ischemia, can cause life time disability. However, we could successfully eradicate these diseases through regeneration. To give you an example, there was this 80+year-old patient, who had coronary artery disease in his 70’s. However, after we treated him with our regenerative therapy for half a year, the doctors could not detect his disease any more, and they thought that there was something wrong with their EKG machine. To give you another example, pulmonary fibrosis, a disease that I had before, had caused asthma in me since my childhood. After I treated myself with our regenerative therapy, the disease is gone from my body and I no longer suffer from asthma. Please note here that what happened is not the so-called anti-fibrosis in medicine, but regeneration of the lungs. These organ disease are mostly due to aging of the cells, which causes the loss of function. By using our regenerative substances the cells are gradually changed and the organ regenerated. Such a unique approach of ours should be welcome by the medical establishment, as we are helping them solve the challenging problems. This approach should be even more welcomed by the patients. Let’s keep in mind that such conversion of the organ diseases by using our approach has a profound significance: we are replacing therapeutics for treating diseases with organ regeneration, which goes beyond medical treatment.

9. Conversion of Cancer into a Treatable Disease with MEBO Regenerative Substances
By using MEBO regenerative energy sources we could convert cancer¾the biggest terminal disease¾into a disease that is preventable and treatable. We are not saying that we have completely conquered cancer. Conquering cancer can be done at various levels, such as cellular levels, tissue levels, organ levels, and systemically. We have conducted several clinical studies and obtained valuable experiences. We would not say that we have conquered cancer. Earlier this year we told the public that it would take us 5 years to conquer cancer, but to do so we need to get support from various parts of the society. Currently we are focusing on those terminal cancer patients who have given up medical treatment and at the end-of-life stage. The results we obtained from these patients who have been treated with our regenerative substances indicate that cancer can be controlled. Such a control of cancer is different from the control of cancer with chemotherapy. The control by chemotherapy is limited and for the terminal patients they would normally die within 5 years after the treatment. Clinically we have successfully converted cancer from terminal to treatable. At the cellular levels, we have demonstrated that we have successfully conquered cancer, as shown in our lung cancer cell experiments publicized earlier. If one does not believe our results, we could allow them to repeat our experiments. When we say that it would take 5 years to validate that we could conquer cancer, this timeline is not randomly picked by us, but factually based. Normally cancer patients would not survive for more than 5 years. In order to truly conquer cancer, we need to focus on prevention. As we demonstrated in our cellular experiments, none of the normal cells could be transformed into cancer cells in the presence of MEBO regenerative substances. In the clinic we need to have at least 5 years to demonstrate the same effect. Currently we are unable to conduct clinical studies of a large population. However, in 5 years, we could use the results of our members who are using MEBO regenerative substances to demonstrate that cancer is preventable. In addition, when the terminal cancer patients in our current studies are completely recovered, we can say that terminal cancer is treatable. What is a terminal disease? A terminal disease is one that is untreatable. What we are doing now is to convert such an untreatable disease into a treatable one. We have a pancreatic cancer patient in Hong Kong who has been taking our regenerative substances. It has been 9 years and his cancer has never re-occurred. Although we have not been able to completely eliminate the large rumor mass, for some of our patients who have lived with tumors for 5 years, the tumor mass has been decreasing in size.

III. Regeneration and Restoration of Non-Injured/Diseased Organs
As far I have been talking about injury due to various causes, such as trauma and diseases. Now I will talk about non-injured organs, about how to use regeneration and restoration in situ to halt aging, retard aging, and to extend life span. This task is one important aspect of MEBO’s endeavors. For the medical treatment of injured organs, we have revolutionized the field and established a brand new medical system. For this part, we have built up a strong medical network of clinicians and will take over the world using our innovative and superior technologies. The other part of MEBO’s endeavors is the nourishment of the human body through regeneration, a concept new to the world and largely considered as impossible by others. For example, many know that gastro-intestinal villi can re-grow after injury, but do not know whether lost villi due to aging and degeneration will re-grow or not. But, we already confirmed this clinically. Although we are not exactly sure what substances inside the body are controlling this regeneration, we attempted to explain this phenomenon using our concept of potentially regenerative cells (PRCs) that essentially confers a second life to the body. The performance of the functions of a human life is dependent on the functions of cells in the tissues and organs. Once the cells are aged, the functions will be reduced. Thus we conclude that the reduction in function represents aging of the cells. What we need to do is to keep the cell young. However, we are not using any hormones like traditional medicine which requires injection of insulin when the body lacks insulin, or injection of epinephrine when the body lack epinephrine. We provide nutrients to the cells through absorption of the digestive tract, i.e., we provide bricks to the cells to build the buildings themselves. When we study the systemic functions of the body, we focus on the cells, the smallest unit of life. We study the growth and regulation of cells within the environment of the body and apply the knowledge back to the body by providing the body the necessary nutrients. Such a research approach has been validated in our clinical practice.
We can say that based on the animal results we obtained from rats fed with MEBO regenerative substances, we have made an important contribution to the advancement of human life sciences. We have demonstrated that all tissues and organs of the rats fed with MEBO regenerative substances retained youthful morphology whereas the control animals aged normally after 500 days of experiments. These results are real experimental data. Although it has not been possible for us to monitor the changes of the human body fed with MEBO regenerative substances over the next 300 years, locally in the body we have obtained encouraging results. For example, we found that by taking the with MEBO regenerative substances, the aged, degenerative intestinal mucosa of humans can be reverted back to a more youthful state, which indicates that the aged organs of a human body can be rejuvenated. This can be accomplished within half a year in humans! MEBO has achieved this level, which is unthinkable for others. This is far more important than anti-aging. MEBO regenerative substances can not only halt the aging process but also reverse the effects of aging, as shown in the restorationof the aged GI tract in humans. These results will shock the world. What we have achieved is all based on regeneration and nourishment of the human body, and our scientific system is truly applicable to humans.
By developing these innovative technologies and inventing the regenerative substances as energy sources for human body regeneration, MEBO has built a brand new world of regeneration, ranging from the outside to the inside of the body, from the old to the young people, from tough to terminal diseases, from maintaining human safety to extension of life span. The MEBO world is open to the scientists and doctors who want to learn how to achieve regeneration in the human body, to those people who feel hopeless about pharmaceutics, and to the people who are pursuing longevity.

 
Copyright © MEBO International Group. All Rights Reserved Beijing ICP 05068194